Перевод и анализ слов искусственным интеллектом
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- как употребляется слово
- частота употребления
- используется оно чаще в устной или письменной речи
- варианты перевода слова
- примеры употребления (несколько фраз с переводом)
- этимология
joining-region gene segment - перевод на русский
общая лексика
J-сегмент гена (иммуноглобулина)
общая лексика
отрезок прямой
сегмент
геометрия
отрезок
![The [[RNA silencing suppressor p19]] from [[tomato bushy stunt virus]], a protein encoded by an overprinted gene. The protein specifically binds [[siRNA]]s produced as part of the plant's [[RNA silencing]] defense against viruses.<ref name="ye_2003" />](https://commons.wikimedia.org/wiki/Special:FilePath/1R9F tombusvirus p19.png?width=200 "The [[RNA silencing suppressor p19]] from [[tomato bushy stunt virus]], a protein encoded by an overprinted gene. The protein specifically binds [[siRNA]]s produced as part of the plant's [[RNA silencing]] defense against viruses.<ref name=\"ye_2003\" />")
![A [[cladogram]] indicating the likely evolutionary trajectory of the gene-dense pX region in [[human T-lymphotropic virus 1]] (HTLV1), a [[deltaretrovirus]] associated with blood cancers. This region contains numerous overlapping genes, several of which likely originated ''de novo'' through overprinting.<ref name="pavesi_2013" />](https://commons.wikimedia.org/wiki/Special:FilePath/Pavesi ploscompbio 2013 fig4.png?width=200 "A [[cladogram]] indicating the likely evolutionary trajectory of the gene-dense pX region in [[human T-lymphotropic virus 1]] (HTLV1), a [[deltaretrovirus]] associated with blood cancers. This region contains numerous overlapping genes, several of which likely originated ''de novo'' through overprinting.<ref name=\"pavesi_2013\" />")
общая лексика
перекрывающийся (с другими последовательностями ДНК) ген
Определение
Википедия
V(D)J recombination is the mechanism of somatic recombination that occurs only in developing lymphocytes during the early stages of T and B cell maturation. It results in the highly diverse repertoire of antibodies/immunoglobulins and T cell receptors (TCRs) found in B cells and T cells, respectively. The process is a defining feature of the adaptive immune system.
V(D)J recombination in mammals occurs in the primary lymphoid organs (bone marrow for B cells and thymus for T cells) and in a nearly random fashion rearranges variable (V), joining (J), and in some cases, diversity (D) gene segments. The process ultimately results in novel amino acid sequences in the antigen-binding regions of immunoglobulins and TCRs that allow for the recognition of antigens from nearly all pathogens including bacteria, viruses, parasites, and worms as well as "altered self cells" as seen in cancer. The recognition can also be allergic in nature (e.g. to pollen or other allergens) or may match host tissues and lead to autoimmunity.
In 1987, Susumu Tonegawa was awarded the Nobel Prize in Physiology or Medicine "for his discovery of the genetic principle for generation of antibody diversity".
